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Journal of Pharmaceutical Research

Article

Optimization of Pharmaceutical Product Formulation by Factorial Designs: Case Studies
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Journal of Pharmaceutical Research

Year: 2016, Volume: 15, Issue: 4, Pages: 105-109

Original Article

Optimization of Pharmaceutical Product Formulation by Factorial Designs: Case Studies

Abstract

Optimization of a product or process is determination of best possible composition or operating conditions resulting in its optimal performance. Optimization techniques are relatively new to the practice of pharmacy. Optimization using factorial designs is an efficient technique used in formulation optimization. Factorial experiments with two level factors are used widely because they are easy to design, efficient to run, straight forward to analyze, and full of information. Five case studies, in which optimization was performed by factorial design are discussed.

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