Journal of Pharmaceutical Research
DOI: 10.18579/jopcr/v17.4.aarsha
Year: 2018, Volume: 17, Issue: 4, Pages: 1-8
Original Article
Aarsha Joby1, Allu Jaya George1, Anjali A Nair1, Prannoy Shanker1, Rajeswari R 1,2,∗, Mahesh N S 3, Shashidhar G2
1Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Carmelaram Varthur Hobli, Bengaluru, Karnataka, India
2Department of General Medicine, MVJ Medical College and Research Hospital, Bengaluru, Karnataka
3Department of Tuberculosis and Respiratory Medicine, MVJ Medical College and Research Hospital, Bengaluru, Karnataka
Objectives: This study aimed to assess the impact of pharmacist-assisted patient counselling for improving medication adherence and quality of life in patients with pulmonary tuberculosis. Methodology : This prospective educational interventional study was conducted in Bangalore's TB Units/DOTS centers to educate patients about TB and medication adherence. Patients were educated, and baseline QOL was measured using the WHO-BREF scale. High-risk patients were identified, and pharmacist counselling was implemented. The impact of counselling on adherence and QOL was also assessed. Findings: A total of 164 individuals participated in the study, with 2 deaths and 5 dropouts, resulting in a final sample size of 157 patients. Among these 157 patients, 37 (23%) demonstrated adherence to the prescribed treatment, 20 (13%) were at risk of nonadherence, and 100 (64%) were classified as nonadherent. The impact of patient counselling on medication adherence was found to be significant (p < 0.0001). Additionally, patients' quality of life scores were affected, particularly in the physical domain, followed by the psychological domain. Following counseling, there was a statistically significant improvement in QOL scores, with a p-value of <0.0001*. Novelty: Pharmacist-assisted patient counselling has a statistically significant impact on improving medication adherence and QOL in patients with pulmonary TB.
Keywords: Pulmonary Tuberculosis, Nonadherence, DOTS, QOL
© 2018 Published by Krupanidhi College of Pharmacy. This is an open-access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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