Journal of Pharmaceutical Research

Abstract

This study was conducted to investigate the antioxidant effect of the ethanolic extracts of the leaves of Glycosmis pentaphylla, Bauhinia variegata and the whole plant of Leucas aspera. The antioxidant activity was evaluated by various antioxidant assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,22 -azinobis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), nitric oxide and hydrogen peroxide (H2O2) scavenging method. The antioxidant activities were compared to standard antioxidant ascorbic acid. Ethanolic crude extract of the plant Leucas aspera showed maximum significant antioxidant activity in DPPH, ABTS, nitric oxide and H2O2 scavenging methods. The findings of the present study suggested that all the three plants could be a potential natural source of antioxidants and could have greater importance as therapeutic agent in preventing or slowing oxidative stress related degenerative diseases.