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Journal of Pharmaceutical Research

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Studies of Antibacterial Activity of the Seed Extract of Solanum surattense Burm. F .
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Journal of Pharmaceutical Research

DOI: 10.18579/jopcr/v21i4.22.24

Year: 2022, Volume: 21, Issue: 4, Pages: 123-127

Original Article

Studies of Antibacterial Activity of the Seed Extract of Solanum surattense Burm. F .

Menavath Tulasi Ram Naik​ ✉ 1 , Sai Kushal Gunturu 1 , Afzal Basha Shaik 1 , Yadlapalli Jaya Prasanth Babu 1 , Sardena Siyonu Kumari 1

1 Department of Pharmaceutical Analysis, Vignan Pharmacy College, Vadlamudi, Guntur, A.P, 522213, India

Corresponding author ✉: [email protected]

Creative Commons License

Abstract

 

Crude Flavonoids extracted from crushed seeds of dried ripe fruits of Solanum surattense Burm F. were screened for antimicrobial activity against two bacteria – Streptococcus mutans and Aggregatibacter actinomycetemcomitans – which were found to be major contributers for occurrence of Dental caries. Minimum inhibitory concentration, Minimum bactericidal concentration, and Time Kill curve of the extract against each sensitive test pathogen, were evaluated. The flavonoid extract showed good antimicrobial activity against Streptococcus mutans than towards Aggregatibacter actinomycetemcomitans. MIC & MBC of Streptococcus mutans is 25µg/mL & 25µg/mL respectively. MIC & MBC of Aggregatibacter actinomycetemcomitans is 50µg/mL & 50µg/mL respectively. Time Kill Curve of Streptococcus mutans and Aggregatibacter actinomycetemcomitans was 2hr and 2hr respectively.

 

Keywords: ­ Solanum surattense, Streptococcus mutans, Aggregatibacter actinomycetemcomitans, Minimum inhibitory concentration, Minimum bactericidal concentration, Time kill curve

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Copyright

© 2022 Published by Krupanidhi College of Pharmacy. This is an open-access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/) 

  • 04 March 2023

Year: 2022, Volume: 21, Issue: 4


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