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Journal of Pharmaceutical Research

Article

A Brief Review on Sustained Release Matrix Type Drug Delivery System
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Journal of Pharmaceutical Research

Year: 2017, Volume: 16, Issue: 3, Pages: 282-289

Original Article

A Brief Review on Sustained Release Matrix Type Drug Delivery System

Abstract

Purpose: A review on sustained release drug delivery using polymer matrix with emphasis on its contemporary usage and future trends.Approach: An introduction to sustained release drug delivery system (SR DDS), followed by its rationale, advantages, disadvantages, criteria of a drug to be met to formulate sustained release formulations, classification of matrix tablets, classification of polymers, its mechanism and recent advancements.Finding: Recent studies indicate that sustained delivery for a very long period, in terms of months is possible using suitable polymer matrices. Also, challenging drug candidates such as proteins are now successfully delivered as sustained release dosage forms.Conclusion: Sustained release DDS, since 1940s has evolved in different types of dosage forms for sustained effect but future scope will be to treat chronic diseases providing sustained effect.

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