A Brief Review on Sustained Release Matrix Type Drug Delivery System

Mayur Karvekar; Arshad Bashir Khan

doi:10.18579/jpcrkc/2017/16/3/118769

Article

A Brief Review on Sustained Release Matrix Type Drug Delivery System

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Journal of Pharmaceutical Research

DOI: 10.18579/jpcrkc/2017/16/3/118769

Year: 2017, Volume: 16, Issue: 3, Pages: 282-289

Original Article

A Brief Review on Sustained Release Matrix Type Drug Delivery System

Mayur Karvekar *, Arshad Bashir Khan

Department of Pharmaceutics, Krupanidhi College of Pharmacy, #12/1, Chikkabellandur, Carmelaram Post, Varthur Hobli, Bangalore - 560035, KA, India

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Purpose: A review on sustained release drug delivery using polymer matrix with emphasis on its contemporary usage and future trends.Approach: An introduction to sustained release drug delivery system (SR DDS), followed by its rationale, advantages, disadvantages, criteria of a drug to be met to formulate sustained release formulations, classification of matrix tablets, classification of polymers, its mechanism and recent advancements.Finding: Recent studies indicate that sustained delivery for a very long period, in terms of months is possible using suitable polymer matrices. Also, challenging drug candidates such as proteins are now successfully delivered as sustained release dosage forms.Conclusion: Sustained release DDS, since 1940s has evolved in different types of dosage forms for sustained effect but future scope will be to treat chronic diseases providing sustained effect.

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