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A Review on 1,2,3 - Triazole & Piperazine Derivatives with Various Biological Activities
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Journal of Pharmaceutical Research

DOI: 10.18579/jopcr/v22.3.23.43

Year: 2023, Volume: 22, Issue: 3, Pages: 113-123

Review Article

A Review on 1,2,3 - Triazole & Piperazine Derivatives with Various Biological Activities

C Geethapriya Loganathan1,*, Karthickeyan Krishnan2, S D Vachala3, Deeparani Urolagin4, J Vijayakumar5

1Research scholar, Department of Pharmaceutical Chemistry, VISTAS, Pallavaram, Chennai, 600043
2Professor and Head, Department of Pharmacy Practice, VISTAS, Pallavaram, Chennai, 600043
3Professor and Head, Department of Pharmaceutical Chemistry, RR College of Pharmacy, Chikkabanavara, Bangalore, 560090
4Professor and Head, Department of Pharmacology, RR College Of Pharmacy, Chikkabanavara, Bangalore, 560090
5Asstistant Professor, RR College of Pharmacy, Department of Pharmacology, Chikkabanavara, Bangalore, 560090

*Corresponding Author
Email: [email protected]

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

The largest family of organic molecules in organic chemistry are heterocyclic compounds. A heterocyclic compound is created when an oxygen, nitrogen, sulphur, or atom of a similar element is included in place of a carbon atom. Heterocyclic compounds play a crucial role in daily living. It has a wide scope of uses in agrochemicals and medicinal chemistry. One of a pair of chemical compounds known as triazoles and Piperazine, with the molecular formula C2H3N3 and C5H5N. A fundamental aromatic heterocyclic scaffold is 1,2,3-triazole and piperazine. Because of its structural characteristics, these moiety’s are valuable in material science and due to its extensive application in chemistry, these can also be synthesized from readily available compounds. This literature review sheds light on the fact that 1,2,3-triazole and piperazine of hetero compounds are profoundly receptive and are known to possess potent diverse activities like, analgesic, anti-HIV, antimalarial, antiviral, anti-inflammatory, anticancer, antibacterial, antifungal, anthelmintic, and so forth. In conclusion numerous biological actions of the Piperazine and 1,2,3-Triazole derivatives of heterocyclic compounds were detailed and reviewed in this review.

Keywords: 1,2,3 - Triazole; Biological activities; Piperazine; Anticancer Activity

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© 2023 Published by Krupanidhi College of Pharmacy. This is an open-access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/) 

  • 03 January 2024

Year: 2023, Volume: 22, Issue: 3


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