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Journal of Pharmaceutical Research

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A Review on CNS Effects of Abelmoschus moschatus
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Journal of Pharmaceutical Research

DOI: 10.18579/jpcrkc/2016/15/1/93741

Year: 2016, Volume: 15, Issue: 1, Pages: 1-5

Original Article

A Review on CNS Effects of Abelmoschus moschatus

M. Giri *, J. Vivek , K. Mahati
  • Department of Pharmacology, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Bangalore-560035, India
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Purpose:Traditional and complementary medicine has helped discover several medicinally important herbs, understand their mechanism of action and use them as drugs to treat serious medical conditions. In the current review, the role of one such herbal extract, Abelmoschus mochatus (AM) in CNS disorders will be detailed.Approach: Published articles from Pubmed and other sources were used to review and compile the CNS effects of AM.Findings: AM seed extract has shown potent anti-oxidant effects leading to its protective effect in neurological disorders. In addition, it also shows antidepressant, anxiolytic, antiepileptic and sedative properties in animal models.Conclusion: AM can be used as an adjuvant therapy in neurological and psychiatric conditions. Research into the precise mechanisms underlying the CNS effects of Abelmoschus moschatus will aid its use in myriad CNS conditions.

References

  • Mukherjee PK, Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. Journal of Ethnopharmacology. 2006 Jan 3; 103(1):25-35.

  • Christina AJ, Muthumani P. Phytochemical investigation and antilithiatic activity of Abelmoschus moschatus medikus. Int. J. Pharm. Pharm. Sci. 2013; 5(1):108-13.

  • Cherniack EP, Senzel RS, Pan CX. Correlates of use of alternative medicine by the elderly in an urban population. The Journal of Alternative & Complementary Medicine. 2001; 7(3):277-80.

  • Scheuing DR, Szekeres E, Bromberg S, inventors; The Clorox Company, assignee. Natural silver disinfectant compositions. United States patent US 8,637,088. 2014 Jan 28.

  • Bajpai A, Ojha JK, Sant HR. Medicobotany of the Varanasi District, Uttar Pradesh, India. International Jurnal of Pharmacognosy. 1995 Jan 1; 33(2):172-6.

  • Liu IM, Tzeng TF, Liou SS. Abelmoschus moschatus (Malvaceae), an aromatic plant, suitable for medical or food uses to improve insulin sensitivity. Phytotherapy Research. 2010 Feb 1; 24(2):233-9.

  • Abhishek B, Sumeet D, Balakrishnan BR.Morphological and anatomical studies of medicinal seeds of the Abelmoschus moschatus Medik.International Journal of Pharmacy Teaching and Practices. 2013; 4(3): 765-7.

  • Kutlu T, Y?ld?r?m I, K?rbag S. Comparison of Ant?microbial Activity of Methanol and Ethanol Extracts of Abelmoschus Moschatus Dry Flowers.Issues. 2014 ; 1(1).

  • Rajeswara R, Syamasundar K, Rajput D, Nagaraju G, Adinarayana G. Potential species of medicinal plants for cultivation in deccan region.

  • Grenand P, Pr�vost MF, Fleury M. Le voyage discret des plantes. Abelmoschus moschatus (Malvaceae) et Zingiber zerumbet (Zingiberaceae) en Am�rique tropicale. Revue d'ethno�cologie. 2012 ; 20(1).

  • Oudhia P. My experiences with world's top ten Indian medicinal plants: Glimpses of research at farmer's field in Chhattisgarh (India). InAbstract Workshop-cum-Seminar on Sustainable Agriculture for 21st Century, IGAU, Raipur, India 2001 Jan; 20-21

  • Oudhia P, Tripathi RS. The possibilities of commercial cultivation of rare medicinal plants in Chhattisgarh (India). In Abstract. VII National Science Conference, Bhartiya Krishi Anusandhan Samittee, Directorate of Cropping System Research, Meerut, India 2001 Apr; 12-14.

  • Rastogi RP, Mehrotra BN. Compendium of Indian medicinal plants. Central Drug Research Institute; 1990.

  • Srivastava UC. Ambrette seed. Advances in Horticulture. 1995; 11:887-97.

  • Pareek SK, Gupta V, Bhat KC, Negi KS, Sharma N. Medicinal and aromatic plants. Plant genetic resources: horticultural crops. Narosa Publishing House, New Delhi. 2005:279-308.

  • Gul MZ, Bhakshu LM, Ahmad F, Kondapi AK, Qureshi IA, Ghazi IA. Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays. BMC complementary and alternative medicine. 2011 Aug 17; 11(1):1.

  • Tewari S. Agriculture Diversification: Medicinal and Aromatic Plants. Agriculture Diversification: Problems and Perspectives. 2010, p-140.

  • Panda H. Medicinal plants cultivation & their uses. Asia Pacific Business Press Inc.; 2002.

  • Prajapati ND, Purohit SS, Sharma AK, Kumar T. Medicinal plants. Agrobios published company, 3rd edition, India. 2003, p-353.

  • Rane RV, Meenakshi K, Shah M, George IA.Biological synthesis of silver nanoparticles using Abelmoschus moschatus. Indian Journal of Biotechnology. 2014 ;13:342-6.

  • Gul MZ, Bhakshu LM, Ahmad F, Kondapi AK, Qureshi IA, Ghazi IA. Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays. BMC complementary and alternative medicine. 2011 ;11(1):1.

  • Liu IM, Tzeng TF, Liou SS. Abelmoschus moschatus (Malvaceae), an aromatic plant, suitable for medical or food uses to improve insulin sensitivity. Phytotherapy Research. 2010 ;24(2):233-9.

  • Abhishek KS, Sanjiv S, Chandel HS. Evaluation of hepatoprotective activity of Abelmoschus moschatus seed in paracetamol induced hepatotoxicity on rat. IOSR Journal of Pharmacy. 2012 ;2(5):43-50.

  • Christina AJ, Muthumani P. Phytochemical investigation and antilithiatic activity of Abelmoschus moschatus medikus. Int. J. Pharm. Pharm. Sci. 2013; 5(1):108-13.

  • Nandhini S, Vadivu R, Jayshree N. Memory strengthening activity on seeds of Abelmoschus moschatus. Int J Res Pharm Chem. 2014; 4(2):346-50.

  • Christina AJ, Muthumani P. Phytochemical investigation and antilithiatic activity of Abelmoschus moschatus medikus. Int. J. Pharm.Pharm. Sci. 2013; 5(1):108-13.

  • Arokiyaraj S, Choi SH, Lee Y, Bharanidharan R, Hairul-Islam VI, Vijayakumar B, Oh YK, DineshKumar V, Vincent S, Kim KH. Characterization of Ambrette Seed Oil and Its Mode of Action in Bacteria. Molecules. 2014; 20(1):384-95.

  • Dokka MK, Seva L, Davuluri SP. Antifungal activity of trypsin inhibitors from the seeds of Abelmoschus moschatus. International Journal of Pharmaceutical Sciences and Research. 2015; 6(9):3920.

  • Sheik HS, Vedhaiyan N, Singaravel S. Evaluation of Abelmoschus moschatus seed extract in psychiatric and neurological disorders. International Journal of Basic & Clinical Pharmacology. 2014; 3(5):845-53.

  • Uttara B, Singh AV, Zamboni P, Mahajan RT. Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Current neuropharmacology. 2009; 7(1):65-74.

  • American Psychiatric Association. DSM-III-R: Diagnostic and statistical manual of mental disorders. American Psychiatric Association; 1980.

  • Kessler RC, Ruscio AM, Shear K, Wittchen HU. Epidemiology of anxiety disorders. In Behavioral neurobiology of anxiety and its treatment 2009, p21. Springer Berlin Heidelberg.

  • Kovess-Masfety V, Alonso J, Brugha TS, Angermeyer MC, Haro JM, Sevilla-Dedieu C. Differences in lifetime use of services for mental health problems in six European countries. Psychiatric Services. 2007.

  • Rao BV, Srikumar BN, Rao BS. Herbal Remedies to Treat Anxiety Disorders. Anxiety. 2009; 85.

  • Madhusudanan M. Psychiatric symptoms in neurological practice. Annals of Indian Academy of Neurology. 2006; 9(2):72.

  • Schmidt D, Schachter SC. Drug treatment of epilepsy in adults. BMJ. 2014 Feb 28; 348(254) :130-136.

  • 01 January 2016

Year: 2016, Volume: 15, Issue: 1


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