Analytical Validation of \'Murcchana\' on the Stability and Phytochemical Profile of Sunthi Ghrita: A Comparative Study

Rohit Gohel; Ebin T U

doi:10.18579/jopcr/v25.i 2.106

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Journal of Pharmaceutical Research

DOI: 10.18579/jopcr/v25.i2.106

Year: 2026, Volume: 25, Issue: 2, Pages: 124-129

Original Article

Analytical Validation of 'Murcchana' on the Stability and Phytochemical Profile of Sunthi Ghrita: A Comparative Study

Rohit Gohel^1*, Ebin T U²

¹PG Scholar, Department of Rasa Shastra Evam Bhaishajya Kalpana, Parul Institute of Ayurved, Parul University, Vadodara, Gujarat, India
²Assistant Professor, Department of Rasa Shastra Evam Bhaishajya Kalpana, Parul Institute of Ayurved, Parul University, Vadodara, Gujarat, India

*Corresponding Author
Email: [email protected]

Abstract

Sneha Kalpana is a dosage form where herbal, mineral or animal drugs are processed in lipid bases like ghee, oil, animal fats. Murcchana is considered as a refining process practiced in Sneha kalpana to enhance their potency, providing odour, enhances stability. Sunti Ghrita (ghee) is one such ghrita-based formulation described in Bhaishajya Ratnavali indicated in. Though it is widely practiced, a thorough analysis or phytochemical profiling is not available till present. There are four formulations: Goghrita, Murcchita Ghrita, Murcchita Sunthi Ghrita and Amurcchita Sunthi Ghrita. Sneha Kalpana principles for the preparation of the four samples. Analytical parameters, like acid value, rancidity, pH etc were tested and Phytochemical profiling was performed through HPTLC. Murcchita Sunthi Ghrita was the stable among all the formulations. It had lowest acid value, lowest peroxide value and the lowest moisture content among all the four samples, indicating its enhanced stability. HPTLC phytochemical analysis emphasized the probable presence of gallic acid, zingerone and curcumin. They are primarily recognized as potent antioxidants and anti-inflammatory agents. The findings concluded that Murcchana may enhance the stability of ghrita by lowering the factors like peroxide value, moisture content and acid value. The present study gives ample proof that traditional refining method, ‘murcchana’ of lipid resources such as ghee, oil etc through herbal drugs is expected to hold a unique potential in enhancing the stability and boosting the potency of these resources into dosage forms.

Keywords: Sunti Ghrita, Murcchana, Sneha Kalpana, HPTLC

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