M. U. Adikwu 1*, O. Okorie 2, A. A. Attama 1
- Drug Delivery Research Unit, Department of Pharmaceutics, University of Nigeria, Nsukka 410001, Nigeria
- Department of Pharmaceutical Technology & Industrial Pharmacy, University of Nigeria, Nsukka 410001, Nigeria
Abstract
The pharmacodynamic effects of metformin in a mucoadhesive delivery system of detarium gum are presented. The gum compacts alone without the drug showed blood glucose lowering capacity. The combinations showed marked antidiabetic effect in streptozotocin-induced diabetic rat models.
